报告题目：New Strategiesfor Ruthenium Catalyzed C-C Formation
报告人：张敬博士,（Department of Chemistry,University of California, Berkeley, CA, 94720）
时间：2016年4月27日(周三)上午10：00 – 11：00
Carbon skeletons are the basis of organicstructures, thus the investigation of new and versatile methods for theconstruction of C–C bonds are fundamental for the development of organicsynthesis and material chemistry. Transition metal catalyzed directfunctionalization of unactivated C-H bonds provides atom-and step-economyroutes to C-C bonds formation to access a variety of building blocks. Theaddition of C-H bond to C-C triple bond via transition metal catalyzed C-H bondactivation provides the most straightforward and economy method to accessvaluable alkenes. However, a long-standing challenge facing this strategy is tocontrol the regio- and stereoselectivity. This presentation describes threeapproaches to deal with this challenge: first, involving the directing groupinto the transformation in a tandem manner; second, developing new catalystswith internal templates; last, utilizing a traceless-removable directing group.
One of the three approaches: traceless-removable directing group